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KMID : 0648320090150040045
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Journal of The Korean Society of Hypertension
2009 Volume.15 No. 4 p.45 ~ p.53
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Blood Pressure Response to Exercise in Patients with Masked Hypertension
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Hwang Eui-Seock
Lee Sae-Hwan
Lee Chang-Hoon
Park Chong-Hun
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Abstract
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Background: Recent studies have shown that masked hypertension (MHT) is associated with a poor cardiovascular prognosis. Therefore, it is important to discriminate between patients with MHT and those patients with normotension (NT) because they cannot be differentiated by clinic BP measurements. We assessed whether there was any significant difference in the BP reactivity during exercise and the echocardiographic variables between the two BP groups.
Methods: Between February 2004 and October 2005, we enrolled 44 subjects with normotension and 47 subjects with masked hypertension. All the sujects had undergone ambulatory blood pressure monitoring (ABPM) for 24 hours and they had performed a treadmill exercise test. Throughout the exercise test, we measured the BP and heart rate responses to exercise in 2-minute intervals. 2D-Doppler echocardiography was also done in all the patients.
Results: The MHT group had significantly higher values of SBP and DBP than the NT group during exercise testing, including the BP in the baseline sitting position, by a mean of 17.4/9.2 mmHg despite that there were no apparent significant differences in heart rates between both groups. No significant differences in the echocardiographic parameters were observed between the two groups.
Conclusions: We found that the exercise BP was significantly higher in the MHT group during the entire exercise period, including the BP in the baseline sitting state. However, an exaggerated BP response during exercise testing and echocardiography cannot be used as diagnostic tools to discriminate MHT from NT.
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KEYWORD
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treadmill test, masked hypertension, BP resonse
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